Toshishige Shibamoto Selected Research

Hypotension (Low Blood Pressure)

1/2020	Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats.
11/2019	Tonic contraction develops in the colon during anaphylactic hypotension in anesthetized rats.
1/2019	Anaphylaxis stimulates afferent vagal nerve activity and efferent sympathetic nerve activity in the stomach of anesthetized rats.
5/2018	Gastric vascular and motor responses to anaphylactic hypotension in anesthetized rats, in comparison to those with hemorrhagic or vasodilator-induced hypotension.
11/2017	Biphasic Renal Sympathetic Response to Hemorrhagic Hypotension in Mice.
10/2014	Mouse anaphylactic shock is caused by reduced cardiac output, but not by systemic vasodilatation or pulmonary vasoconstriction, via PAF and histamine.
5/2014	Angiotensin II and vasopressin are involved in the defense system against anaphylactic hypotension in anesthetized rats.
1/2014	Effects of anesthetics on the renal sympathetic response to anaphylactic hypotension in rats.
11/2013	MRI reveals edema in larynx (but not in brain) during anaphylactic hypotension in anesthetized rats.
7/2013	Rat hepatic and splanchnic vascular responses to anaphylactic shock, compared with hemorrhagic or vasodilator-induced shock.

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Toshishige Shibamoto Research Topics

Disease

33	Anaphylaxis (Anaphylactic Shock) 01/2020 - 01/2004
24	Hypotension (Low Blood Pressure) 01/2020 - 10/2005
6	Weight Loss (Weight Reduction) 12/2010 - 01/2004
5	Portal Hypertension 10/2013 - 10/2005
4	Shock 07/2013 - 01/2002
3	Body Weight (Weight, Body) 02/2015 - 01/2013
3	Weight Gain 05/2007 - 01/2004
2	Hemorrhage 05/2018 - 07/2013
2	Reperfusion Injury 05/2007 - 01/2004
2	Liver Diseases (Liver Disease) 07/2006 - 01/2004
1	Sepsis (Septicemia) 01/2020
1	Acute Lung Injury 01/2020
1	Bradycardia 11/2017
1	Tachycardia (Tachyarrhythmias) 01/2017
1	Inflammation (Inflammations) 03/2016
1	Obesity 03/2016
1	AIDS-Related Complex (ARC) 01/2015
1	Spasm (Spasms) 01/2014
1	Edema (Dropsy) 11/2013
1	Pathologic Constriction (Stenosis) 04/2013
1	Pulmonary Hypertension 04/2013
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2011
1	Heat Stroke (Heatstroke) 09/2010
1	Liver Cirrhosis (Hepatic Cirrhosis) 06/2008
1	Metrorrhagia (Spotting) 12/2007
1	Ischemia 05/2007

Drug/Important Bio-Agent (IBA)

26	OvalbuminIBA 01/2020 - 01/2004
24	AntigensIBA 01/2020 - 01/2004
9	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2018 - 01/2004
7	NG-Nitroarginine Methyl Ester (L-NAME)IBA 09/2018 - 04/2005
5	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2018 - 01/2011
5	Platelet Activating FactorIBA 01/2008 - 01/2004
4	Histamine (Histamine Dihydrochloride)FDA Link 01/2020 - 04/2005
4	Vasodilator Agents (Vasodilators)IBA 05/2018 - 07/2006
4	Propranolol (Inderal)FDA LinkGeneric 01/2018 - 01/2011
4	Nitric Oxide Synthase (NO Synthase)IBA 02/2009 - 04/2005
3	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 05/2018 - 07/2006
3	Norepinephrine (Noradrenaline)FDA LinkGeneric 10/2013 - 04/2005
3	LipidsIBA 05/2007 - 01/2004
2	LeukotrienesIBA 01/2020 - 12/2007
2	Epinephrine (Adrenaline)FDA LinkGeneric 01/2018 - 03/2011
2	capsazepineIBA 11/2017 - 01/2017
2	LeptinIBA 01/2015 - 01/2013
2	arginine methyl esterIBA 02/2009 - 04/2005
2	TCV 309IBA 12/2007 - 12/2005
2	pranlukastIBA 12/2007 - 12/2005
2	15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidIBA 07/2006 - 01/2004
1	Angiopoietin-2IBA 01/2020
1	SecretagoguesIBA 01/2020
1	AngiopoietinsIBA 01/2020
1	CytokinesIBA 01/2020
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020
1	gamma-Aminobutyric Acid (GABA)IBA 01/2018
1	Aminobutyrates (Aminobutyric Acid)IBA 01/2018
1	Atenolol (Tenormin)FDA LinkGeneric 01/2017
1	Insulin (Novolin)FDA Link 03/2016
1	OrnithineIBA 02/2015
1	AngiotensinsIBA 05/2014
1	Vasopressins (Vasopressin)IBA 05/2014
1	Angiotensin IIIBA 05/2014
1	Captopril (Capoten)FDA LinkGeneric 05/2014
1	Anesthetics (Anesthetic Agents)IBA 01/2014
1	Pentobarbital (Nembutal)FDA Link 01/2014
1	Sphingosine-1-Phosphate ReceptorsIBA 11/2013
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 11/2013
1	Small Interfering RNA (siRNA)IBA 01/2013
1	salicylhydroxamic acid (SHAM)IBA 03/2011
1	CatecholaminesIBA 01/2011
1	EndotoxinsIBA 09/2010
1	pimagedine (aminoguanidine)IBA 02/2009
1	7-nitroindazoleIBA 02/2009
1	IsoenzymesIBA 02/2009
1	Endothelin-1 (Endothelin 1)IBA 06/2008
1	Diphenhydramine (Benadryl)FDA LinkGeneric 01/2008
1	CV 6209IBA 01/2008
1	seratrodastIBA 12/2007
1	KetanserinIBA 12/2007
1	leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA 12/2007
1	Indomethacin (Indometacin)FDA LinkGeneric 12/2007
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 12/2007
1	Soluble Guanylyl CyclaseIBA 07/2007
1	OxadiazolesIBA 07/2007
1	Methylene Blue (Methylthioninium Chloride)FDA Link 07/2007
1	p-Methoxy-N-methylphenethylamineIBA 07/2007
1	Oxygen (Dioxygen)IBA 07/2006
1	Leukotriene D4IBA 07/2006
1	ThromboxanesIBA 07/2006
1	Nicorandil (SG 75)IBA 10/2005

Therapy/Procedure

13	Intravenous Injections 01/2020 - 10/2005
6	Controlled Hypotension 05/2018 - 07/2007
5	Denervation 01/2018 - 01/2014
2	Sympathectomy (Sympathectomies) 01/2019 - 01/2016
2	Vagotomy 11/2017 - 01/2017
2	Injections 01/2017 - 01/2014
2	Hepatectomy 11/2007 - 10/2005
1	Anesthesia 01/2014
1	Chemical Sympathectomy 10/2013
1	Surgical Portacaval Shunt (Portacaval Anastomosis) 03/2011
1	Therapeutics 01/2011
1	Ligation 11/2007